Jakub Dybas, Ph.D. 

Head of the Laboratory of Raman Spectroscopy
e-mail: jakub.dybas@jcet.eu

Jakub Dybaś obtained his PhD in Chemistry in 2019 at the Faculty of Chemistry of the Jagiellonian University. Since 2013, he has been scientifically associated with the Jagiellonian Centre for Experimental Therapeutics (JCET), where he has been Head of the Laboratory of Raman Spectroscopy. In his research, he is focused on the use of Raman spectroscopy and resonance Raman spectroscopy to detect pathological alterations of red blood cells and to better understand the molecular structure of hemoglobin adducts. Between 03-09.2019 he was visiting researcher at the University of Saint Louis in the United States, broadening his knowledge in resonance Raman spectroscopy. He was principal investigator of two projects awarded by National Science Center in Poland (Preludium 12 and Etiuda 5), and was a laureate of the START 2022 programme of the Foundation for Polish Science. Currently he leads OPUS21 entitled “In search of the unexplored aspects of ferric heme protein-dependent regulation of nitric oxide signalling in the erythrocyte and vessel wall” carried out in JCET between 2022 – 2025. In 2023, he was awarded a scholarship by the Ministry of Science and Higher Education scholarship for outstanding young scientists. 

Selected recent publications

  • Dybas, J., Chiura, T., Marzec, K. M., & Mak, P. J. (2021). Probing Heme Active Sites of Hemoglobin in Functional Red Blood Cells Using Resonance Raman Spectroscopy. The Journal of Physical Chemistry B, 125(14), 3556–3565. https://doi.org/10.1021/acs.jpcb.1c01199
  • Stepanenko, T., Zajac, G., Czajkowski, A., Rutkowska, W., Górecki, A., Marzec, K.M., Dybas, J., (2023). Sulfhemoglobin under the spotlight – Detection and characterization of SHb and HbFeIII–SH. Biochimica et Biophysica Acta (BBA) – Molecular Cell Research, 119378. https://doi.org/10.1016/j.bbamcr.2022.119378.

More: https://orcid.org/0000-0003-2202-5068