JCET

The results of the 21st edition of the SONATA competition, organised by the National Science Centre in Kraków, have been announced. One of the winners was Dr Grzegorz Zając, who received funding for the project: “CHIR4AD: Improving the diagnosis of Alzheimer’s disease – chiroptical probes for early detection of protein aggregates”.

The primary objective of this project is to identify spectroscopic and chiroptical biomarkers associated with protein aggregates on erythrocytes and to determine how their supramolecular chirality reflects early pathological changes in Alzheimer’s disease. Novel circularly polarized luminescence (CPL) and resonance Raman optical activity (RROA) molecular probes will be designed and tested as fast, selectively sensitive diagnostic tools for detecting aggregates in blood samples from disease murine models.