Jakub Dybas, PhD, University Professor
e-mail: jakub.dybas@uj.edu.pl
Field: red blood cells, hemoglobin adducts, blood cell biomedicine, biophysics, biospectroscopy, resonance Raman spectroscopy
Jakub Dybas obtained his doctorate in chemical sciences in 2019 at the Faculty of Chemistry, Jagiellonian University. Since 2013, he has been scientifically associated with the Jagiellonian Centre for Experimental Therapeutics (JCET), where, from July 2021 to December 2025, he served as the head of the Raman Spectroscopy Laboratory; he is currently employed as a university professor and a leader in the blood cell research area.
In his research, he focuses on the use of biospectroscopy methods, particularly resonance Raman spectroscopy, to detect pathological changes in erythrocytes and to better understand the molecular structure of haemoglobin adducts in the progression of erythropathy. Between March and September 2019, he completed an internship at Saint Louis University in the United States, deepening his knowledge of resonance Raman spectroscopy. He has been the principal investigator of two projects funded by the National Science Centre (Preludium 12 and Etiuda 5) and was awarded the START programme 2022 by the Foundation for Polish Science. Currently, he is leading the OPUS21 project titled “In search of the unexplored aspects of ferric heme protein-dependent regulation of nitric oxide signalling in the erythrocyte and vessel wall” carried out at JCET from 2022 to 2026. In 2023, he was awarded a scholarship from the Minister of Science and Higher Education for outstanding young scientists.
Dr Jakub Dybas’s scientific output includes a total of 42 full-text scientific publications, of which 38 are original works. Additionally, he is a co-author of 3 chapters in monographs in English and 2 chapters in monographs in Polish. Jakub is the primary author of 16 works (15 of which are in Q1 according to Scopus), and in 7 of these, he also serves as the corresponding author. His Hirsch index is 16.
ORCID ID: 0000-0003-2202-5068
SCOPUS AUTHOR ID: 56816846400
WEB OF SCIENCE RESEARCHER ID: AAW-3063-2021
RESEARCH TEAM
Ewa Szczęsny-Małysiak, PhD – post-doctoral researcher
e-mail: ewa.szczesny@uj.edu.pl
Amanda Bartkowiak, PhD – post-doctoral researcher
e-mail: amanda.bartkowiak@uj.edu.pl
SELECTED PUBLICATIONS
E. Szczesny-Malysiak, A. Bartkowiak, K. Bulat and J. Dybas*, NO-induced change in the oxidation state of cytochrome c in endothelial cells monitored by resonance Raman imaging, Free Radical and Biology Medicine, 2025, 239, 472–482, https://doi.org/10.1016/j.freeradbiomed.2025.08.010
E. Szczesny‐Malysiak, A. Bartkowiak and J. Dybas*, Label‐free tracking of cytochrome C oxidation state in live cells by resonance Raman imaging, FEBS Letters, 2024, 598, 1981–1988. https://doi.org/10.1002/1873-3468.14905
T. Stepanenko, G. Zajac, A. Czajkowski, W. Rutkowska, A. Górecki, K.M. Marzec, J. Dybas*, Sulfhemoglobin under the spotlight – Detection and characterization of SHb and HbFeIII–SH, Biochimica et Biophysica Acta (BBA) – Molecular Cell Research, 2023, 1870, 119378. https://doi.org/1
0.1016/j.bbamcr.2022.119378J. Dybas*, T. Chiura, K. M. Marzec, P. J. Mak*, Probing Heme Active Sites of Hemoglobin in Functional Red Blood Cells Using Resonance Raman Spectroscopy, Journal of Physical Chemistry B, 2021, 125, 14, 3556–3565. https://doi.org/10.1021/acs.jpcb.1c01199.