{"id":2494,"date":"2025-02-28T10:33:10","date_gmt":"2025-02-28T09:33:10","guid":{"rendered":"https:\/\/jcet.eu\/new_en\/?p=2494"},"modified":"2025-02-28T10:33:11","modified_gmt":"2025-02-28T09:33:11","slug":"sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction","status":"publish","type":"post","link":"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/","title":{"rendered":"SONATA BIS 16: 4B for LDs: Biodiversity, Biogenesis, Biodegradation and Biomedicine of lipid droplets in age-dependent vascular dysfunction"},"content":{"rendered":"\n

The National Science Centre in Krak\u00f3w has announced the results of the SONATA BIS 14, and among the winners is dr. hab. Marta Pacia. The project will address the importance of lipid droplets in aging endothelium.<\/strong><\/p>\n\n\n\n

\"\"<\/a><\/figure>\n\n\n\n\n\n\n\n

Endothelial cells play a crucial role in regulating the transport of lipids from the blood. Under physiological conditions, endothelial cells effectively “buffer” excess lipids by converting them into lipid droplets (LDs) during the postprandial phase, when the body processes and absorbs consumed food. Shortly after their formation, these LDs undergo lipolysis in a process controlled by a set of enzymes and LDs-associated proteins. However, it remains unexplored whether age-altered endothelial cells retain the ability to effectively buffer lipids under conditions of postprandial lipid overload. Today, most people consume too much fatty food and spend the majority of the day in the postprandial phase. The endothelium’s inability to cope with excess lipids in the blood is considered a prerequisite for the development of endothelial dysfunction, and consequently, cardiovascular diseases.<\/p>\n\n\n\n

Results<\/a><\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

The National Science Centre in Krak\u00f3w has announced the results of the SONATA BIS 14, and among the winners is dr. hab. Marta Pacia. The project will address the importance of lipid droplets in aging endothelium.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-2494","post","type-post","status-publish","format-standard","hentry","category-varia"],"acf":[],"yoast_head":"\nSONATA BIS 16: 4B for LDs: Biodiversity, Biogenesis, Biodegradation and Biomedicine of lipid droplets in age-dependent vascular dysfunction » JCET<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"SONATA BIS 16: 4B for LDs: Biodiversity, Biogenesis, Biodegradation and Biomedicine of lipid droplets in age-dependent vascular dysfunction » JCET\" \/>\n<meta property=\"og:description\" content=\"The National Science Centre in Krak\u00f3w has announced the results of the SONATA BIS 14, and among the winners is dr. hab. Marta Pacia. The project will address the importance of lipid droplets in aging endothelium.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/\" \/>\n<meta property=\"og:site_name\" content=\"JCET\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/jcet.eu\/\" \/>\n<meta property=\"article:published_time\" content=\"2025-02-28T09:33:10+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-02-28T09:33:11+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/jcet.eu\/new_en\/wp-content\/uploads\/2025\/02\/We-are-having-a-baby-girl-1.png\" \/>\n\t<meta property=\"og:image:width\" content=\"810\" \/>\n\t<meta property=\"og:image:height\" content=\"450\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Agnieszka Gudek\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Agnieszka Gudek\" \/>\n\t<meta name=\"twitter:label2\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/\"},\"author\":{\"name\":\"Agnieszka Gudek\",\"@id\":\"https:\/\/jcet.eu\/new_en\/#\/schema\/person\/aa0014c9ab5728df0c0977a4c5985ed9\"},\"headline\":\"SONATA BIS 16: 4B for LDs: Biodiversity, Biogenesis, Biodegradation and Biomedicine of lipid droplets in age-dependent vascular dysfunction\",\"datePublished\":\"2025-02-28T09:33:10+00:00\",\"dateModified\":\"2025-02-28T09:33:11+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/\"},\"wordCount\":183,\"publisher\":{\"@id\":\"https:\/\/jcet.eu\/new_en\/#organization\"},\"image\":{\"@id\":\"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/jcet.eu\/new_en\/wp-content\/uploads\/2025\/02\/We-are-having-a-baby-girl-1.png\",\"articleSection\":[\"Varia\"],\"inLanguage\":\"en-GB\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/\",\"url\":\"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/\",\"name\":\"SONATA BIS 16: 4B for LDs: Biodiversity, Biogenesis, Biodegradation and Biomedicine of lipid droplets in age-dependent vascular dysfunction » JCET\",\"isPartOf\":{\"@id\":\"https:\/\/jcet.eu\/new_en\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/jcet.eu\/new_en\/wp-content\/uploads\/2025\/02\/We-are-having-a-baby-girl-1.png\",\"datePublished\":\"2025-02-28T09:33:10+00:00\",\"dateModified\":\"2025-02-28T09:33:11+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/#breadcrumb\"},\"inLanguage\":\"en-GB\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/#primaryimage\",\"url\":\"https:\/\/jcet.eu\/new_en\/wp-content\/uploads\/2025\/02\/We-are-having-a-baby-girl-1.png\",\"contentUrl\":\"https:\/\/jcet.eu\/new_en\/wp-content\/uploads\/2025\/02\/We-are-having-a-baby-girl-1.png\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/jcet.eu\/new_en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"SONATA BIS 16: 4B for LDs: Biodiversity, Biogenesis, Biodegradation and Biomedicine of lipid droplets in age-dependent vascular dysfunction\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/jcet.eu\/new_en\/#website\",\"url\":\"https:\/\/jcet.eu\/new_en\/\",\"name\":\"JCET\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/jcet.eu\/new_en\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/jcet.eu\/new_en\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-GB\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/jcet.eu\/new_en\/#organization\",\"name\":\"Jagiellonian Centre for Experimental Therapeutics (JCET)\",\"url\":\"https:\/\/jcet.eu\/new_en\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\/\/jcet.eu\/new_en\/#\/schema\/logo\/image\/\",\"url\":\"http:\/\/jcet.eu\/new_en\/wp-content\/uploads\/2022\/06\/JCET-logo.png\",\"contentUrl\":\"http:\/\/jcet.eu\/new_en\/wp-content\/uploads\/2022\/06\/JCET-logo.png\",\"width\":715,\"height\":401,\"caption\":\"Jagiellonian Centre for Experimental Therapeutics (JCET)\"},\"image\":{\"@id\":\"https:\/\/jcet.eu\/new_en\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/jcet.eu\/\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/jcet.eu\/new_en\/#\/schema\/person\/aa0014c9ab5728df0c0977a4c5985ed9\",\"name\":\"Agnieszka Gudek\",\"sameAs\":[\"http:\/\/admin\"],\"url\":\"https:\/\/jcet.eu\/new_en\/author\/agag\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"SONATA BIS 16: 4B for LDs: Biodiversity, Biogenesis, Biodegradation and Biomedicine of lipid droplets in age-dependent vascular dysfunction » JCET","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/","og_locale":"en_GB","og_type":"article","og_title":"SONATA BIS 16: 4B for LDs: Biodiversity, Biogenesis, Biodegradation and Biomedicine of lipid droplets in age-dependent vascular dysfunction » JCET","og_description":"The National Science Centre in Krak\u00f3w has announced the results of the SONATA BIS 14, and among the winners is dr. hab. Marta Pacia. The project will address the importance of lipid droplets in aging endothelium.","og_url":"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/","og_site_name":"JCET","article_publisher":"https:\/\/www.facebook.com\/jcet.eu\/","article_published_time":"2025-02-28T09:33:10+00:00","article_modified_time":"2025-02-28T09:33:11+00:00","og_image":[{"width":810,"height":450,"url":"https:\/\/jcet.eu\/new_en\/wp-content\/uploads\/2025\/02\/We-are-having-a-baby-girl-1.png","type":"image\/png"}],"author":"Agnieszka Gudek","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Agnieszka Gudek","Estimated reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/#article","isPartOf":{"@id":"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/"},"author":{"name":"Agnieszka Gudek","@id":"https:\/\/jcet.eu\/new_en\/#\/schema\/person\/aa0014c9ab5728df0c0977a4c5985ed9"},"headline":"SONATA BIS 16: 4B for LDs: Biodiversity, Biogenesis, Biodegradation and Biomedicine of lipid droplets in age-dependent vascular dysfunction","datePublished":"2025-02-28T09:33:10+00:00","dateModified":"2025-02-28T09:33:11+00:00","mainEntityOfPage":{"@id":"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/"},"wordCount":183,"publisher":{"@id":"https:\/\/jcet.eu\/new_en\/#organization"},"image":{"@id":"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/#primaryimage"},"thumbnailUrl":"https:\/\/jcet.eu\/new_en\/wp-content\/uploads\/2025\/02\/We-are-having-a-baby-girl-1.png","articleSection":["Varia"],"inLanguage":"en-GB"},{"@type":"WebPage","@id":"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/","url":"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/","name":"SONATA BIS 16: 4B for LDs: Biodiversity, Biogenesis, Biodegradation and Biomedicine of lipid droplets in age-dependent vascular dysfunction » JCET","isPartOf":{"@id":"https:\/\/jcet.eu\/new_en\/#website"},"primaryImageOfPage":{"@id":"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/#primaryimage"},"image":{"@id":"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/#primaryimage"},"thumbnailUrl":"https:\/\/jcet.eu\/new_en\/wp-content\/uploads\/2025\/02\/We-are-having-a-baby-girl-1.png","datePublished":"2025-02-28T09:33:10+00:00","dateModified":"2025-02-28T09:33:11+00:00","breadcrumb":{"@id":"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/#breadcrumb"},"inLanguage":"en-GB","potentialAction":[{"@type":"ReadAction","target":["https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/"]}]},{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/#primaryimage","url":"https:\/\/jcet.eu\/new_en\/wp-content\/uploads\/2025\/02\/We-are-having-a-baby-girl-1.png","contentUrl":"https:\/\/jcet.eu\/new_en\/wp-content\/uploads\/2025\/02\/We-are-having-a-baby-girl-1.png"},{"@type":"BreadcrumbList","@id":"https:\/\/jcet.eu\/new_en\/2025\/02\/28\/sonata-bis-16-4b-for-lds-biodiversity-biogenesis-biodegradation-and-biomedicine-of-lipid-droplets-in-age-dependent-vascular-dysfunction\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/jcet.eu\/new_en\/"},{"@type":"ListItem","position":2,"name":"SONATA BIS 16: 4B for LDs: Biodiversity, Biogenesis, Biodegradation and Biomedicine of lipid droplets in age-dependent vascular dysfunction"}]},{"@type":"WebSite","@id":"https:\/\/jcet.eu\/new_en\/#website","url":"https:\/\/jcet.eu\/new_en\/","name":"JCET","description":"","publisher":{"@id":"https:\/\/jcet.eu\/new_en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/jcet.eu\/new_en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-GB"},{"@type":"Organization","@id":"https:\/\/jcet.eu\/new_en\/#organization","name":"Jagiellonian Centre for Experimental Therapeutics (JCET)","url":"https:\/\/jcet.eu\/new_en\/","logo":{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/jcet.eu\/new_en\/#\/schema\/logo\/image\/","url":"http:\/\/jcet.eu\/new_en\/wp-content\/uploads\/2022\/06\/JCET-logo.png","contentUrl":"http:\/\/jcet.eu\/new_en\/wp-content\/uploads\/2022\/06\/JCET-logo.png","width":715,"height":401,"caption":"Jagiellonian Centre for Experimental Therapeutics (JCET)"},"image":{"@id":"https:\/\/jcet.eu\/new_en\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/jcet.eu\/"]},{"@type":"Person","@id":"https:\/\/jcet.eu\/new_en\/#\/schema\/person\/aa0014c9ab5728df0c0977a4c5985ed9","name":"Agnieszka Gudek","sameAs":["http:\/\/admin"],"url":"https:\/\/jcet.eu\/new_en\/author\/agag\/"}]}},"_links":{"self":[{"href":"https:\/\/jcet.eu\/new_en\/wp-json\/wp\/v2\/posts\/2494","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jcet.eu\/new_en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jcet.eu\/new_en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jcet.eu\/new_en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/jcet.eu\/new_en\/wp-json\/wp\/v2\/comments?post=2494"}],"version-history":[{"count":1,"href":"https:\/\/jcet.eu\/new_en\/wp-json\/wp\/v2\/posts\/2494\/revisions"}],"predecessor-version":[{"id":2496,"href":"https:\/\/jcet.eu\/new_en\/wp-json\/wp\/v2\/posts\/2494\/revisions\/2496"}],"wp:attachment":[{"href":"https:\/\/jcet.eu\/new_en\/wp-json\/wp\/v2\/media?parent=2494"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jcet.eu\/new_en\/wp-json\/wp\/v2\/categories?post=2494"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jcet.eu\/new_en\/wp-json\/wp\/v2\/tags?post=2494"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}