Kamil Przyborowski, Ph.D.

Head of the SONATA Project, NCN
e-mail: kamil.przyborowski@jcet.eu

Kamil Przyborowski graduated from the Faculty of Pharmacy at the Medical University of Bialystok, in 2019 he obtained the degree of Doctor of Medical Sciences at the Faculty of Medicine of the Jagiellonian University Medical College. The subject of his doctoral thesis, which he defended with honors, was the role of vascular endothelial adaptation in regulation of exercise capacity, platelet activation and post-exercise endothelial function in mice. During his doctorate, he was the principal investigator of the project PRELUDIUM funded by the polish National Science Center (NCN) entitled: “The role of reactive oxygen species (ROS) generated during a maximal exercise by endothelial NOX2 and NOX4 in the regulation of post-exercise oxidant stress, post-exercise haemostasis and exercise capacity”. He has been working in Jagiellonian Center for Experimental Therapeutics (JCET) since 2014. He was awarded with fellowships to conduct research at the Medical University of Hamamatsu in Japan (2013-2014) and the Center for Thrombosis and Hemostasis (CTH) in Mainz in Germany (2022). Currently, his scientific interests focus on the role of protein disulfide isomerases (PDIs) in the regulation of platelet activation and thrombus formation. He is the principal investigator of the project SONATA entitled: “Inhibition of protein disulfide isomerases as a strategy for reduction of prothrombotic state in atherosclerosis; therapeutic implications”, funded by the NCN.

Selected recent publication

  • Vascular Nitric Oxide-Superoxide Balance and Thrombus Formation after Acute Exercise. Przyborowski K, Proniewski B, Czarny J, Smeda M, Sitek B, Zakrzewska A, Zoladz JA, Chlopicki S. Med Sci Sports Exerc. 2018 Jul;50(7):1405-1412. doi: 10.1249/MSS.0000000000001589.
  • Protein disulfide isomerase-A1 regulates intraplatelet reactive oxygen species-thromboxane A2 -dependent pathway in human platelets. Przyborowski K, Kurpinska A, Wojkowska D, Kaczara P, Suraj-Prazmowska J, Karolczak K, Malinowska A, Pelesz A, Kij A, Kalvins I, Watala C, Chlopicki S. J Thromb Haemost. 2022 Jan;20(1):157-169. doi: 10.1111/jth.15539.

More: https://orcid.org/0000-0002-8526-945X