Patrycja Kaczara, Ph.D., DSc

Head of the Laboratory of EPR Spectroscopy
e-mail: patrycja.kaczara@jcet.eu

Patrycja Kaczara obtained her PhD in 2012 at the Faculty of Biochemistry, Biophysics and Biotechnology of the Jagiellonian University, and passed habilitation proceeding in a discipline of biology in 2022 at Jagiellonian University. Since 2013, she has worked at the Jagiellonian Centre for Experimental Therapeutics (JCET), where she has been a head of the Laboratory of EPR Spectroscopy. Her scientific interests are focused on cellular energy metabolism. She completed short internships at several scientific institutions abroad: Medical College of Wisconsin (Milwaukee, USA; 2010), INSERM – Faculty of Medicine (Creteil, France; 2014) and University College London (London, Great Britain; 2015), where she studied oxidative stress and energy metabolism in in vitro cells. She was a principal investigator in a project awarded by the National Science Centre in Poland (SONATA 3) and currently she leads OPUS 21 entitled: “Normalization of energy metabolism as a way to develop innovative antithrombotic therapies” carried out in JCET (2022 – 2025).

Selected recent publications

  • Kaczara, B. Sitek, K. Przyborowski, A. Kurpińska, K. Kuś, M. Stojak, S. Chłopicki „Antiplatelet effect of carbon monoxide is mediated by NAD+ and ATP depletion” Arteriosclerosis, Thrombosis, and Vascular Biology (2020) 40(10):2376-2390, DOI: 10.1161/ATVBAHA.120.314284
  • Kaczara, R. Motterlini, G.M. Rosen, B. Augustynek, P. Bednarczyk, A. Szewczyk, R. Foresti, S. Chłopicki “Carbon monoxide released by CORM-401 uncouples mitochondrial respiration and inhibits glycolysis in endothelial cells: A role for mitoBKCa channels” BBA Bioenergetics (2015) 1847(10): 1297-1309, DOI: 10.1016/j.bbabio.2015.07.004

More: https://orcid.org/0000-0003-0106-4172